Zebrafish Leukemia

Identification And Localization Of The Abelson Oncogene In ...
Identification and Localization of the Abelson Oncogene in . Zebrafish, Danio rerio. Richard C. de Triquet. 1, Brandon S. Carpenter. 2, Ted Zerucha. 1,* of leukemia and is also linked to the progression of certain lung and breast cancers. Despite ... Access Doc

Mangosteen - Benefits Of This Tropical Fruit
Mangosteen (Garcinia mangostana L.) is a tropical fruit said to offer a number of health benefits. Often touted for its antioxidant effects, mangosteen is sometimes referred to as a "superfruit." ... Read Article

MODELING PEDIATRIC CANCERS IN ZEBRAFISH
MODELING PEDIATRIC CANCERS IN ZEBRAFISH Presenter: Kyle West L Batchelor, K West, Background: T cell cancers are relatively common pediatric malignancies, with T cell acute lymphoblastic leukemia (T-ALL) and lymphoblastic lymphoma (T-LBL) both afflicting hundreds of US ... Document Viewer

Zebrafish: A New Model For Human Disease
How to generate zebrafish disease models . Activate or inhibit protein function by drug treatment Yu et al., Nature Chem Biol., (2008) control MoTP T cell lineage acute lymphoblastic leukemia (T-ALL) • Aggressive hematologic tumors resulting from malignant ... Doc Viewer

Connexin - Wikipedia, The Free Encyclopedia
An open gap junction, composed of six identical connexin proteins. Each of these six units is a single polypeptide which passes the membrane four times (referred to as four-pass transmembrane proteins). ... Read Article

Zebrafish Etv7 Regulates Red Blood Cell Development Through ...
Promote pre-B-cell leukemia in mice. It is normally expressed in the Zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway Anita M. Quintana1,*, Fabrizio Picchione1, Ramon I. Klein Geltink1, ... Read Content

Chapter 16 Zebrafish As A Model To Study Stem Cells In ...
16 Zebrafish as a Model to Study Stem Cells in Development, Disease, and Cancer 285 hematopoietic wave occurs in two intraembryonic sites: (1) in the ventral meso- ... Fetch This Document

Pten Mediates Myc Oncogene Dependence In A Conditional ...
Zebrafish that became moribund with leukemia before the 8-wk time point were euthanized and classified into the progression category. Number of fish analyzed per condition: 4HT, n = 8; +4HT, n = 13. on August 23, 2011 jem.rupress.org Downloaded from ... Read Document

Chronic Myelogenous Leukemia Research Program - CDMRP
Chronic Myelogenous Leukemia Research Program Vision To eradicate chronic myelogenous leukemia (CML). Mission To identify and sponsor basic and funded the establishment of both mouse and zebrafish models of CML to better study the disease. ... Return Document

The Pu.1 Promoter Drives Myeloid Gene Expression In zebrafish
The pu.1 promoter drives myeloid gene expression in zebrafish and the Leukemia and Lymphoma Society Specialized Center of Research (SCOR) NUMBER 5 PU.1 PROMOTERAND GENE EXPRESSION IN ZEBRAFISH 1293 From www.bloodjournal.org by guest on November 3, 2014. For personal use only. ... Retrieve Full Source

T Cell Receptor - Wikipedia, The Free Encyclopedia
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) [1] that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. ... Read Article

Efficient Genome-wide Mutagenesis Of zebrafish Genes By ...
Efficient genome-wide mutagenesis of zebrafish mutagenic effect is seen when murine leukemia virus integrates specifically in the first intron of genes but not in other introns. Three of 19 gene inactivation events had embryonic defects. ... Read Document

Zebrafish As A Model To Assess Cancer Heterogeneity ...
Recipient of the same species) of zebrafish T-cell acute lymphoblastic leukemia (T-ALL) to select for aggressive disease, and observed that CNAs in serially passaged T-ALL encompassed oncogenes and tumor suppressor genes known to be crucial for ... Fetch This Document

Zebrafish Take The Stage In Cancer Research - Oxford Journals
A month and died of leukemia around 90 days of age. “The model was very reminis-cent of T-cell lymphoma progression to leukemia in mammals,” Look says. Zebrafish Take the Stage in Cancer Research By Mary Beckman C ancer biologists are dangling a ... Access Doc

National Human Genome Research Institute (NHGRI) Patent ...
National Human Genome Research Institute (NHGRI) Patent-Pending Technology Available for Licensing New Targeted Leukemia Therapy NHGRI Invention Number: E-060-2011 function in zebrafish, and suppressed leukemia progression in mouse models of CBF leukemia. Potential Commercial Applications ... Retrieve Content

In Vivo Imaging Of Macrophage Patrolling In zebrafish - YouTube
Random patrolling of macrophages in a Tg(mpeg1: In vivo imaging of macrophage patrolling in zebrafish The Company of Biologists. Zebrafish Injection Leukemia Cells - Duration: 3:04. CircadianLab 1,044 views. 3:04 ... View Video

Highly Efficient Germ-line Transmission Of Proviral ...
Highly efficient germ-line transmission of proviral insertions in zebrafish based on the Moloney murine leukemia virus and the envelope protein of the vesicular stomatitis virus. This virus was ... Get Doc

Zebrafish Mll GeneIsEssentialforHematopoiesis S
Zebrafish embryogenesis, particularly hematopoiesis. Mll de- The mixed lineage leukemia (MLL) gene, a human homolog of Drosophila melanogaster Trithorax (Trx), was originally identifiedthroughitsinvolvementinin-framereciprocaltrans- ... Retrieve Doc

Zebrafish: An In Vivo Model For The Study Of Human Diseases
Zebrafish: An in Vivo Model for the Study of Human Diseases. International Journal of Genetics and Genomics. Vol. 1, No. 1, 2013, pp. 6-11. doi: Very recently, an acute myeloid leukemia (AML) zebrafish model was created by expressing a human AML1-ETo translocation fusion gene. [48]. This ... Doc Retrieval

Zebrafish Mll Is Essential For Haematopoiesis
Zebrafish embryogenesis, in particular, haematopoiesis. Mll depletion caused The mixed lineage leukemia (MLL) gene, a human homolog of Drosophila melanogaster Trithorax (Trx), was originally identified through its involvement in ... Read More

Through The Looking Glass: Visualizing Leukemia Growth ...
Through the Looking Glass: Visualizing Leukemia Growth, Migration, and Engraftment Using Fluorescent Transgenic Zebrafish (Article begins on next page) ... Access Full Source

Expression Of The Cytoplasmic NPM1 Mutant (NPMc+) Causes The ...
4 The zebrafish is a powerful vertebrate disease model system. Several human and murine oncogenes involved in leukemogenesis cause leukemia and disrupt normal ... Visit Document

Leukemic Cell Xenograft In zebrafish Embryo For Investigating ...
Due to the limited number of transgenic zebrafish leukemia models, we explored human leukemic cell xenograft in zebrafish embryos. Human leukemic cell lines and blast cells sorted from patients with acute myelogenous leukemia were injected ... Fetch Content

Review Article Zebrafish As A Model For The Study Of Human ...
Review Article Zebrafish as a Model for the Study of Human Myeloid Malignancies Jeng-WeiLu, 1 Meng-ShanHsieh, 1 Heng-AnLiao, 1 Yi-JuYang, 1 Yi-JungHo, 2,3 andLiang-InLin 1,4 ... Fetch Here