Xiap Leukemia

The Histone Deacetylase Inhibitor LAQ824 Induces Human ...
The Histone Deacetylase Inhibitor LAQ824 Induces Human Leukemia Cell Death through a Process Involving XIAP Down-Regulation, Oxidative Injury, and the Acid Sphingomyelinase- ... Access Doc

XIAP Downregulation Promotes Caspase ... - Leukemia Research
976 B.Z. Carter et al. / Leukemia Research 37 (2013) 974–979 Fig. 2. Inhibition of XIAP expression and chemical inhibition of proteasome activity similarly upregulate the expression of proteasome component genes. ... Fetch Doc

Umashaver - YouTube
2015 Immuno-Hematology Symposium Ben Liao Award Presentation-- Dr. Kelly Walkovich and Dr. Jim Connelly The Impact of EBV Infecting T-cells-- Dr. Adam DuVall Thank you, Immuno-Hem ... View Video

Antagonizing XIAP-mediated Caspase-3 Inhibition:Achilles’heel ...
IAP (XIAP), the best studied member of the IAP family, is differentially upregulat- range of solid tumor and leukemia cell lines in vitro, suppressed clonogenic sur-vival of tumor cells, and were effective in tumor xenograft models. This is the first ... Document Viewer

Simultaneous Targeting Of P-gp And XIAP With SiRNAs Increases ...
P-gp overexpressing chronic myeloid leukemia cells to imatinib. Keywords: XIAP, P-gp, imatinib mesylate, Drug resistance Introduction Chronic myeloid leukemia (CML) is characterized by a translocation between chromosomes 9 and 22, giving ... View Document

XIAP And CIAP1 Amplifications Induce Beclin 1- Dependent ...
XIAP and cIAP1 amplifications induce Beclin 1- leukemia and Hodgkin lymphoma (19). XIAP and cIAP1 are highly expressed in almost all of a series of 60 human cancer cell lines studied (20). Here we describe that high levels of XIAP and cIAP1 expression induce the ... Fetch This Document

Triterpenoid Electrophiles (Avicins) Suppress Heat Shock ...
XIAP in leukemia cells could have important implications in the treatment of drug-resistant neoplasia and inflammatory disorders. INTRODUCTION Several lines of evidence indicate that cancer is a multistep process that reveals genetic changes driving a normal cell to ... Get Content Here

Apoptosis In leukemia: From Molecular Pathways To Targeted ...
A specific subgroup of AML patients where XIAP levels are increased and contribute to disease pathogenesis. In these patients, inhibiting XIAP may be useful therapeutically. ... Access Document

Addition Of AEG35156 XIAP Antisense Oligonucleotide In ...
Overexpression of XIAP confers chemoresistance in leukemia cell lines and its chemical8,9 or genetic inhibition10 induces cell death and sensitizes cells to chemotherapy. In some11,12 but not all studies,13,14 patients with the highest levels of XIAP have a worse ... Document Retrieval

Berberine Induces Apoptosis In P53-Null Leukemia Cells By ...
Berberine • Apoptosis • Leukemia • XIAP Abstract Background: Berberine exerts anticancer activities both in vitro and in vivo through different mechanisms. However, the underlying molecular mechanisms of berberine induced p53-independent apoptosis remain unclear. ... Fetch Full Source

Simultaneous Activation Of P53 And Inhibition Of XIAP Enhance ...
Simultaneous activation of p53 and inhibition of XIAPenhance the activation of apoptosis signaling pathways inAML and 6Department of Leukemia, The University of Texas M. D.Anderson Cancer Center, targeting of antiapoptotic XIAP in acute myeloid leukemia. Leukemia. 2003;17:2081-2089. 7. ... Get Doc

Nonlinear Regulation Of Commitment To Apoptosis By ...
Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells 4 Joanna Skommer1, Somkanya C Das2§, Arjun Nair2§, Thomas Brittain1, Subhadip ... Fetch Content

Antisense Oligonucleotides Targeting XIAP Induce Apoptosis ...
Antisense Oligonucleotides Targeting XIAP Induce Apoptosis and Enhance Chemotherapeutic Activity against Human Lung Cancer Cells in Vitro and in Vivo1 ... Get Content Here

Death-associated Protein 6 - Wikipedia, The Free Encyclopedia
Death-associated protein 6 also known as Daxx is a protein that in humans is encoded by the DAXX gene. [1] [2 Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. XIAP NAIP Survivin c-IAP-1 c-IAP-2. ... Read Article

Apoptosis Inducers In Chronic Lymphocytic leukemia
Apoptosis inducers in chronic lymphocytic leukemia Christian Billard1,2 1 INSERM U 872, Centre de Recherche des Cordeliers, Equipe 18, Paris, France IAP (XIAP) appears to be the IAP that has a major role in caspase inactivation [10]. ... Retrieve Content

Embelin Sensitizes Acute Myeloid Leukemia Cells To TRAIL ...
ORIGINAL PAPER Embelin Sensitizes Acute Myeloid Leukemia Cells to TRAIL through XIAP Inhibition and NF-jB Inactivation Tianxin Yang • Jianping Lan • Qiang Huang• ... Get Content Here

Embelin Induces Apoptosis Through Down-regulation Of XIAP In ...
ORIGINAL PAPER Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells Rong Hu • Ke Zhu • Yingchun Li • Kun Yao • Rong Zhang • Huihan Wang • Wei Yang• ... Access Full Source

XIAP And P-glycoprotein Co-expression Is Related To Imatinib ...
K.L. Silva et al. / Leukemia Research 37 (2013) 1350–1358 1355 Fig. 5. Effects of imatinib in P-glycoprotein (Pgp), XIAP and Survivin expressions in K562 (Pgp−) and Lucena (Pgp+) cell lines. ... Fetch Here

Nonlinear Regulation Of Commitment To Apoptosis By ...
ORIGINAL PAPER Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells Joanna Skommer • Somkanya C. Das• ... Fetch This Document

CIAPs And XIAP Reduce RIPKs To Silence - Blood Journal
CIAPs and XIAP reduce RIPKs to silence----- Arnaud Jacquel1 and Patrick Auberger1 1UNIVERSITY OF NICE In this issue of Blood, Wong et al evaluated in acute myeloid leukemia, and increased XIAP expression was found to be XIAP regulate myelopoiesis through cytokine production ... Fetch Document

Apoptosis - Wikipedia, The Free Encyclopedia
Whether this whole process resembles animal apoptosis closely enough to warrant using the name apoptosis (as opposed to the more general Atromentin induces apoptosis in human leukemia U937 cells. [85] Autolysis; Autophagy; Cisplatin; XIAP NAIP Survivin c-IAP-1 c-IAP-2. Apoptosis-inducing ... Read Article

ABT-737 Increases Tyrosine Kinase Inhibitor-induced Apoptosis ...
ABT-737 increases tyrosine kinase inhibitor–induced apoptosis in chronic myeloid leukemia cells through XIAP downregulation and sensitizes CD34þ ... Document Retrieval